Institut für Verfahrenstechnik, Umwelttechnik und Techn. Biowissenschaften
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Wir bitten um Verständnis, dass die Informationen über dieses Projekt derzeit nur in englischer Sprache verfügbar sind.

Goals

  • Automated sampling and analysis by HPLC and enzymatic analyzers in a CHO and microbial processes
  • Facilitate fully automated process monitoring and control, for example..
  • ….Rational media and feed design, monitoring and control… !

Approach

  • Establish on-line analytics with Amino Acids, Vitamins, Sugars, Cells & Product... in real time and as retain samples…
  • Integrate HPLC but also Cedex Hires and Cexed BioHT online
  • Run cultures with CHO and microbial under industrial relevant process conditions

Novelty

  • Robust solutions far beyond academic fields
  • External filtration device
  • Sample with or w/o cells
  • High precision measurements with golden standards only

Outlook

  • Integration in model predictive control context
  • Automated workflows for rational media and feed design
  • Parallalize for multi reactor systems.

 

 

Project overview (click to download)

Contact:

Univ. Prof. Dipl.-Ing. Dr. techn. Christoph Herwig